Pharmacy Technician

1. Which mechanism is most common for drug molecules crossing lipid membranes?

2. Ligand-gated ion channel receptors directly regulate:

3. Pharmacodynamics is best described as the study of:

4.
1. Pharmacokinetics primarily describes:

5. A drug’s ability to cross the blood–brain barrier depends primarily on:

6. First-pass hepatic metabolism most profoundly reduces the bioavailability of drugs given via the:

7. Endocytosis and exocytosis are used to transport:

8. Which route of drug administration is classified as enteral?

9. The “first-pass effect” refers to drug loss during:

10. Which is a parenteral route of administration?

11. An example of “other” routes of administration is:

12. Which process is most responsible for reabsorption of lipid-soluble drugs in the kidney?

13. Active transport of drugs across membranes requires:

14. Which branch of pharmacology studies the effects of drugs on receptors and physiological functions?

15. The primary organ for drug metabolism is the:

16. A major disadvantage of the oral route is:

17. Phase II metabolism typically results in:

18. A pharmacological receptor may include:

19. The half-life of a drug is the time required for its plasma concentration to fall by:

20. Which tissue has the lowest rate of drug distribution based on blood flow?

21. Intracellular receptors for drugs are most likely to:

22. Drug absorption is defined as the transfer of a drug from its site of administration into:

23. The primary site of drug excretion for polar water-soluble metabolites is the:

24. Which of the following best defines pharmacology?

25. Which factor does NOT significantly modify drug absorption?

26. Sublingual administration:

27. Sublingual administration:

28. Enzyme-linked receptors often possess:

29. Drugs bound to plasma proteins are:

30. Which family of receptors uses a seven–transmembrane domain linked to a G-protein?

31. Which physiological barrier is most restrictive to drug movement?

32. A drug with a large apparent volume of distribution (> 100 L) is most likely:

33. Bioavailability (F) is defined as the fraction of an administered dose that:

34. Apparent volume of distribution (Vd) is calculated by:

35. Which route accounts for significant drug excretion of volatile anesthetics?

36. Phase I metabolic reactions most often involve: